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Solution structure of ca-bound S100A4 in complex with non-muscle myosin iia

Analyse Solution structure of ca-bound S100A4 in complex with non-muscle myosin iia in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2LNK
Type
protein
Length
241 residues
Chains
3
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Myosin heavy chain, non-muscle iia; Protein S100-A4
UniProt
P35579, P26447

Structure

solution nmr · 2 distinct chains · 56% helix, 1% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
CMyosin heavy chain, non-muscle iiaprotein3956% helix, 0% strandP35579
A, BProtein S100-A4protein10155% helix, 2% strandP26447

Interfaces

3 interfaces between chains.

  • A–B · 1575 Ų buried · 10 hydrogen bonds · protein-protein
  • C–B · 1307 Ų buried · 14 hydrogen bonds · protein-protein
  • C–A · 994 Ų buried · 13 hydrogen bonds · protein-protein

Compared structures

  • 2LNK · Solution structure of Ca-bound S100A4 in complex with non-muscle myosin IIA · the same entry in another collection · chain C against C, TM-score 1.00
  • P26447 · AlphaFold monomer V2.0 prediction for protein S100-A4 (P26447) · a predicted model of the same protein · chain A against A, TM-score 0.73
  • P35579 · AlphaFold monomer V2.0 prediction for myosin-9 (P35579) · a predicted model of the same protein · chain C against A, TM-score 0.54

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