UniProt P26447
Protein S100-A4 (P26447)
Protein S100-A4 (UniProt P26447): 33 experimental structures on GenesisL1, 3 ligands bound, 26 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P26447
- Protein
- Protein S100-A4
- Experimental structures
- 33
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 26 · 4 records with a druggable one
Structures
33 records of P26447 in the MolNFT archive: 33 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1M31 | Three-Dimensional Solution Structure of Apo-Mts1 | solution nmr | A, B | — | — |
| 1M31 | Three-dimensional solution structure of apo-MTS1 | solution nmr | A, B | — | — |
| 2LNK | Solution structure of Ca-bound S100A4 in complex with non-muscle myosin IIA | solution nmr | A, B | — | — |
| 2LNK | Solution structure of ca-bound S100A4 in complex with non-muscle myosin iia | solution nmr | A, B | — | — |
| 2MRD | Solution structure of human Ca2+-loaded S100A4 cys-free mutant | solution nmr | A, B | — | — |
| 2MRD | Solution structure of human CA2+-loaded S100A4 cys-free mutant | solution nmr | A, B | — | — |
| 2Q91 | Structure of the Ca2+-Bound Activated Form of the S100A4 Metastasis Factor | x-ray diffraction | A, B | — | — |
| 2Q91 | Structure of the CA2+-bound activated form of the S100A4 metastasis factor | x-ray diffraction | A, B | — | — |
| 3C1V | The 1.5 A Crystal structure of Ca2+-bound S100A4 | x-ray diffraction | A, B, C, D | — | — |
| 3C1V | The 1.5 a crystal structure of CA2+-bound S100A4 | x-ray diffraction | A, B, C, D | — | — |
| 3CGA | Crystal structure of metastasis-associated protein S100A4 in the active, calcium-bound form | x-ray diffraction | A, B | — | — |
| 3CGA | Crystal structure of metastasis-associated protein S100A4 in the active, calcium-bound form | x-ray diffraction | A, B | — | — |
| 3KO0 | Structure of the tfp-ca2+-bound activated form of the s100a4 Metastasis factor | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 3KO0 | Structure of the tfp-CA2+-bound activated form of the S100A4 metastasis factor | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | — | — |
| 3M0W | Structure of S100A4 with PCP | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 3M0W | Structure of S100A4 with pcp | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 3ZWH | Ca2+-bound S100A4 C3S, C81S, C86S and F45W mutant complexed with myosin IIA | x-ray diffraction | A, B | — | — |
| 3ZWH | CA2+-bound S100A4 C3S, C81S, C86S and F45W mutant complexed with myosin iia | x-ray diffraction | A, B | — | — |
| 4CFQ | Ca-bound truncated (delta13C) and C3S, C81S and C86S mutated S100A4 complexed with non-muscle… | x-ray diffraction | A, B, C, D | — | — |
| 4CFQ | Ca-bound truncated (DELTA13C) and C3S, C81S and C86S mutated S100A4 complexed with non-muscle… | x-ray diffraction | A, B, C, D | — | — |
| 4CFR | Ca-bound S100A4 C3S, C81S, C86S and F45W mutant complexed with non- muscle myosin IIA | x-ray diffraction | A, B | — | — |
| 4CFR | Ca-bound S100A4 C3S, C81S, C86S and F45W mutant complexed with non- muscle myosin iia | x-ray diffraction | A, B | — | — |
| 4ETO | Structure of S100A4 in complex with non-muscle myosin-IIA peptide | x-ray diffraction | A, B | — | — |
| 4ETO | Structure of S100A4 in complex with non-muscle myosin-iia peptide | x-ray diffraction | A, B | — | — |
| 4HSZ | Structure of truncated (delta8C) S100A4 | x-ray diffraction | A, B, C, D | — | — |
| 4HSZ | Structure of truncated (DELTA8C) S100A4 | x-ray diffraction | A, B, C, D | — | — |
| 5LPU | Crystal structure of Annexin A2 complexed with S100A4 | x-ray diffraction | C, D | CA | 5 (best 0.76) |
| 5LPU | Crystal structure of annexin A2 complexed with S100A4 | x-ray diffraction | C, D | CA | — |
| 6T58 | Structure determination of the transactivation domain of p53 in complex with S100A4 using annexin… | x-ray diffraction | A, B | CA | 14 (best 0.75) |
| 6T58 | Structure determination of the transactivation domain of P53 in complex with S100A4 using annexin… | x-ray diffraction | A, B | CA | — |
| 7PSP | Crystal structure of S100A4 labeled with NU000846b. | x-ray diffraction | A, B | 85Q, CA | 3 (best 0.80) |
| 7PSQ | Crystal structure of S100A4 labeled with NU074381b. | x-ray diffraction | A, C, E, G | CA, 82Q | 4 (best 0.66) |
| P26447 | AlphaFold monomer V2.0 prediction for protein S100-A4 (P26447) | — | — | — |
Ligands
Experiment against prediction
- 6T58 chain B against the predicted model P07355: TM-score 0.99, RMSD 0.92 Å
- 6T58 chain B against the predicted model P07355: TM-score 0.99, RMSD 0.92 Å
- 6T58 chain A against the predicted model P07355: TM-score 0.60, RMSD 1.28 Å
- 6T58 chain A against the predicted model P07355: TM-score 0.60, RMSD 1.28 Å
Elsewhere
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