MolNFT v1 · #42927 · protein
Structure of the C-domain fragment of apo calmodulin bound to the iq motif of NAV1.2
2KXW: “Structure of the C-domain fragment of apo calmodulin bound to the iq motif of NAV1.2”. Solution nmr. MolNFT v1 #42927 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2KXW
- Type
- protein
- Length
- 100 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Calmodulin; Sodium channel protein type 2 subunit alpha
- UniProt
- P07463, P04775
Structure
solution nmr · 2 distinct chains · 59% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Calmodulin | protein | 73 | 55% helix, 10% strand | P07463 |
| B | Sodium channel protein type 2 subunit alpha | protein | 27 | 70% helix, 0% strand | P04775 |
Interfaces
1 interface between chains.
- A–B · 905 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 2KXW · Structure of the C-domain Fragment of apo Calmodulin Bound to the IQ motif of Nav1.2 · the same entry in another collection · chain A against A, TM-score 1.00
- P04775 · AlphaFold monomer V2.0 prediction for sodium channel protein type 2 subunit alpha (P04775) · a predicted model of the same protein · chain B against A, TM-score 0.58
- P07463 · AlphaFold monomer V2.0 prediction for calmodulin (P07463) · a predicted model of the same protein · chain A against A, TM-score 0.53
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07463
- Every structure of UniProt P04775
- Elsewhere: RCSB PDB 2KXW · PDBe 2KXW · UniProt P07463 · UniProt P04775
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