MolNFT v1 · #42905 · RNA

NMR structure of stem-loop 4 from the human 7SK snrna in complex with arginine

2KX8: “NMR structure of stem-loop 4 from the human 7SK snrna in complex with arginine”. Solution nmr, 1 ligand (ARG), 2 pockets (best druggability 0.51). MolNFT v1 #42905 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2KX8
Type: RNA
Length: 42 nucleotides
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 7SK
Ligands: ARG
Pockets: 2 · best druggability 0.51

Structure

solution nmr · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	7SK	rna	42	—	—

Ligands and binding sites

ARG · Arginine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	345	0.51	0.73	20	empty
2	158	0.39	0.74	13	ARG

Compared structures

2KX8 · NMR structure of stem-loop 4 from the human 7SK snRNA in complex with arginine · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2KX8 · PDBe 2KX8

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