GL1X · GenesisL1 explorer

MolNFT v1 · #42587 · protein

Platelet integrin alfaiib-BETA3 transmembrane-cytoplasmic heterocomplex

2KNC · Integrin alpha-iib: “Platelet integrin alfaiib-BETA3 transmembrane-cytoplasmic heterocomplex”. Solution nmr. MolNFT v1 #42587 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
2KNC
Type
protein
Length
133 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Integrin alpha-iib; Integrin beta-3
UniProt
P08514, P05106

Structure

solution nmr · 2 distinct chains · 58% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AIntegrin alpha-iibprotein5450% helix, 0% strandP08514
BIntegrin beta-3protein7963% helix, 0% strandP05106

Interfaces

1 interface between chains.

  • A–B · 709 Ų buried · 0 hydrogen bonds · protein-protein

Compared structures

  • 2KNC · Platelet integrin ALFAIIB-BETA3 transmembrane-cytoplasmic heterocomplex · the same entry in another collection · chain A against A, TM-score 1.00
  • P05106 · AlphaFold monomer V2.0 prediction for integrin beta-3 (P05106) · a predicted model of the same protein · chain B against A, TM-score 0.47
  • P08514 · AlphaFold monomer V2.0 prediction for integrin alpha-iib (P08514) · a predicted model of the same protein · chain A against A, TM-score 0.44

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