MolNFT v1 · #41916 · protein
NMR solution structure of the split pH domain from phospholipase C gamma 2
2K2J · 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase…: “NMR solution structure of the split pH domain from phospholipase C gamma 2”. Solution nmr, 1 pocket (best druggability 0.40). MolNFT v1 #41916 on GenesisL1: 3D structure…
- PDB
- 2K2J
- Type
- protein
- Length
- 117 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2
- EC
- 3.1.4.11
- UniProt
- P16885
- Pockets
- 1 · best druggability 0.40
Structure
solution nmr · 1 distinct chain · 12% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) | protein | 117 | 12% helix, 34% strand | P16885 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 118 | 0.40 | 0.75 | 23 | empty |
Compared structures
- 2K2J · NMR solution structure of the split PH domain from Phospholipase C gamma 2 · the same entry in another collection · chain A against A, TM-score 1.00
- P16885 · AlphaFold monomer V2.0 prediction for 1-phosphatidylinositol 4,5-bisphosphate… · a predicted model of the same protein · chain A against A, TM-score 0.82
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16885
- Elsewhere: RCSB PDB 2K2J · PDBe 2K2J · UniProt P16885
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