MolNFT v1 · #39829 · protein
The structure of a putative RNA methyltransferase of the trmh family from porphyromonas gingivalis.
2I6D · RNA methyltransferase, trmh family: “The structure of a putative RNA methyltransferase of the trmh family from porphyromonas gingivalis.”. X-ray diffraction, 2 pockets (best druggability 0.54). MolNFT v1 #39829 on GenesisL1: 3D…
- PDB
- 2I6D
- Type
- protein
- Length
- 251 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA methyltransferase, trmh family
- EC
- 2.1.1.-
- UniProt
- Q7MW92
- Pockets
- 2 · best druggability 0.54
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA methyltransferase, trmh family (EC 2.1.1.-) | protein | 251 | 33% helix, 24% strand | Q7MW92 |
Ligands and binding sites
- ACY · Acetic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 102 | 0.54 | 0.84 | 22 | empty |
| 2 | 65 | 0.41 | 0.81 | 19 | empty |
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 2I6D · The structure of a putative RNA methyltransferase of the TrmH family from Porphyromonas… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7MW92
- Elsewhere: RCSB PDB 2I6D · PDBe 2I6D · UniProt Q7MW92
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