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The structure of a putative RNA methyltransferase of the trmh family from porphyromonas gingivalis.

Analyse The structure of a putative RNA methyltransferase of the trmh family from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2I6D
Type: protein
Length: 251 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA methyltransferase, trmh family
EC: 2.1.1.-
UniProt: Q7MW92
Pockets: 2 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA methyltransferase, trmh family (EC 2.1.1.-)	protein	251	33% helix, 24% strand	Q7MW92

Ligands and binding sites

ACY · Acetic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	102	0.54	0.84	22	empty
2	65	0.41	0.81	19	empty

Modifications

Observed in the structure: 6 modified (engineered).

Compared structures

2I6D · The structure of a putative RNA methyltransferase of the TrmH family from Porphyromonas… · the same entry in another collection · chain A against A, TM-score 1.00

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7MW92
Elsewhere: RCSB PDB 2I6D · PDBe 2I6D · UniProt Q7MW92

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