MolNFT v1 · #38779 · protein
Discovery of potent, highly selective, and orally bioavailable pyridine carboxamide C-jun NH2-terminal kinase inhibitors
2H96: “Discovery of potent, highly selective, and orally bioavailable pyridine carboxamide C-jun NH2-terminal kinase…”. X-ray diffraction. MolNFT v1 #38779 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2H96
- Type
- protein
- Length
- 735 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P45983, Q9UQF2
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 358 | — | P45983 |
| F, G | — | protein | 10 | — | Q9UQF2 |
| B | — | protein | 357 | — | P45983 |
Compared structures
- 2H96 · Discovery of Potent, Highly Selective, and Orally Bioavailable Pyridine Carboxamide C-jun… · the same entry in another collection · chain A against A, TM-score 1.00
- P45983 · AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase 8 (P45983) · a predicted model of the same protein · chain A against A, TM-score 0.97
- Q9UQF2 · AlphaFold monomer V2.0 prediction for C-jun-amino-terminal kinase- interacting protein 1… · a predicted model of the same protein · chain F against A, TM-score 0.39
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P45983
- Every structure of UniProt Q9UQF2
- Elsewhere: RCSB PDB 2H96 · PDBe 2H96 · UniProt P45983 · UniProt Q9UQF2
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