MolNFT v1 · #38225 · protein
Crystal structure of udp-N-acetylenolpyruvylglucosamine reductase (murb) from thermus caldophilus
2GQT: “Crystal structure of udp-N-acetylenolpyruvylglucosamine reductase (murb) from thermus caldophilus”. X-ray diffraction, 2 ligands (FAD, CA), 2 pockets (best druggability 0.77). MolNFT v1 #38225 on GenesisL1: 3D structure, binding…
- PDB
- 2GQT
- Type
- protein
- Length
- 267 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Udp-N-acetylenolpyruvylglucosamine reductase
- EC
- 1.1.1.158
- Ligands
- FAD, CA
- Pockets
- 2 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 28% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Udp-N-acetylenolpyruvylglucosamine reductase (EC 1.1.1.158) | protein | 267 | 28% helix, 27% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 767 | 0.77 | 0.81 | 71 | FAD |
| 2 | 57 | 0.29 | 0.75 | 17 | empty |
Compared structures
- 2GQT · Crystal Structure of UDP-N-Acetylenolpyruvylglucosamine Reductase (MurB) from Thermus… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2GQT · PDBe 2GQT
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.