The crystallization of reaction center from rhodobacter sphaeroides occurs via a new route

Structure

x-ray diffraction · 3 distinct chains · 52% helix, 9% strand (DSSP).

Ligands and binding sites

• BCL · Bacteriochlorophyll A · ligand · 4 copies · chains L, M
• U10 · Ubiquinone-10 · ligand · 2 copies · chains L, M
• BPH · Bacteriopheophytin A · ligand · 2 copies · chains L, M
• CDL · Cardiolipin · ligand · chains L, M
• FE2 · Fe (II) ion · metal · chains L, M
• CL · Chloride ion · ion · chains M
• LDA · Lauryl dimethylamine-N-oxide · additive · chains H, M

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Interfaces

3 interfaces between chains.

• L–M · 4615 Ų buried · 69 hydrogen bonds · protein-protein
• H–M · 2930 Ų buried · 43 hydrogen bonds · protein-protein
• H–L · 1608 Ų buried · 19 hydrogen bonds · protein-protein

Compared structures

• 2GNU · The crystallization of reaction center from Rhodobacter sphaeroides occurs via a new route · the same entry in another collection · chain L against L, TM-score 1.00
• P0C0Y8 · AlphaFold monomer V2.0 prediction for reaction center protein L chain (P0C0Y8) · a predicted model of the same protein · chain L against A, TM-score 0.99
• P0C0Y9 · AlphaFold monomer V2.0 prediction for reaction center protein M chain (P0C0Y9) · a predicted model of the same protein · chain M against A, TM-score 0.99
• P0C0Y7 · AlphaFold monomer V2.0 prediction for reaction center protein H chain (P0C0Y7) · a predicted model of the same protein · chain H against A, TM-score 0.98

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P0C0Y7
• Every structure of UniProt P0C0Y8
• Every structure of UniProt P0C0Y9
• Elsewhere: RCSB PDB 2GNU · PDBe 2GNU · UniProt P0C0Y7 · UniProt P0C0Y8 · UniProt P0C0Y9