MolNFT v1 · #37387 · protein
Structure of the E. COLI puta proline dehydrogenase domain reduced by dithionite and complexed with proline
2FZN · Bifunctional protein puta, proline dehydrogenase (ec…: “Structure of the E. COLI puta proline dehydrogenase domain reduced by dithionite and complexed with proline”. X-ray diffraction, 2 ligands (FAD, PRO), 4 pockets (best…
- PDB
- 2FZN
- Type
- protein
- Length
- 449 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Bifunctional protein puta, proline dehydrogenase (ec 1.5.99.8) (proline oxidase)
- EC
- 1.5.99.8
- UniProt
- P09546
- Ligands
- FAD, PRO
- Pockets
- 4 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 55% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Bifunctional protein puta, proline dehydrogenase (ec 1.5.99.8) (proline oxidase) (EC 1.5.99.8) | protein | 449 | 55% helix, 10% strand | P09546 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 466 | 0.84 | 0.91 | 41 | FAD, PRO |
| 2 | 166 | 0.51 | 0.78 | 23 | empty |
| 3 | 101 | 0.44 | 0.79 | 24 | empty |
| 4 | 56 | 0.31 | 0.76 | 13 | empty |
Compared structures
- 2FZN · Structure of the E. coli PutA proline dehydrogenase domain reduced by dithionite and… · the same entry in another collection · chain A against A, TM-score 1.00
- P09546 · AlphaFold monomer V2.0 prediction for bifunctional protein puta (P09546) · a predicted model of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09546
- Elsewhere: RCSB PDB 2FZN · PDBe 2FZN · UniProt P09546
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