MolNFT v1 · #33031 · protein
Crystal structure of narbomycin-bound cytochrome P450 pikc (CYP107L1)
2C7X · Cytochrome P450 monooxygenase: “Crystal structure of narbomycin-bound cytochrome P450 pikc (CYP107L1)”. X-ray diffraction, 2 ligands (HEM, NRB), 1 pocket (best druggability 0.87). MolNFT v1 #33031 on GenesisL1: 3D structure, binding…
- PDB
- 2C7X
- Type
- protein
- Length
- 396 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cytochrome P450 monooxygenase
- UniProt
- O87605
- Ligands
- HEM, NRB
- Pockets
- 1 · best druggability 0.87
Structure
x-ray diffraction · 1 distinct chain · 54% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cytochrome P450 monooxygenase | protein | 396 | 54% helix, 10% strand | O87605 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 889 | 0.87 | 0.89 | 88 | HEM, NRB |
Compared structures
- 2C7X · Crystal structure of narbomycin-bound cytochrome P450 PikC (CYP107L1) · the same entry in another collection · chain A against A, TM-score 1.00
- O87605 · AlphaFold monomer V2.0 prediction for cytochrome P450 monooxygenase pikc (O87605) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O87605
- Elsewhere: RCSB PDB 2C7X · PDBe 2C7X · UniProt O87605
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