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Ligand · NRB

NRB · Narbomycin

NRB, Narbomycin (C28 H47 N O7, 509.7 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
NRB
Formula
C28 H47 N O7
Class
ligand
Structures
5
PDB entries
3

Binding sites

NRB in 5 structures; the first of them:

  • 2C7X · Crystal structure of narbomycin-bound cytochrome P450 PikC (CYP107L1) · NRB A1408 · binds ASP50, TRP74, GLU85, LEU93, GLU94, PHE178, VAL179, ALA187 and 13 more
  • 2VZM · Crystal structure of the narbomycin-bound PikC D50N mutant · NRB A1408 · binds GLU85, LEU93, GLU94, PHE178, VAL179, ALA187, GLN188, MET191 and 12 more
  • 8GUE · Crystal Structure of narbomycin-bound cytochrome P450 PikC with the unnatural amino acid… · NRB A502 · binds TRP74, LEU81, GLU85, LEU93, GLU94, PHE178, VAL179, MET191 and 13 more
  • 2C7X · Crystal structure of narbomycin-bound cytochrome P450 pikc (CYP107L1) · NRB A1408 · binds ASP50, TRP74, GLU85, LEU93, GLU94, PHE178, VAL179, ALA187 and 13 more
  • 2VZM · Crystal structure of the narbomycin-bound pikc D50N mutant · NRB A1408 · binds GLU85, LEU93, GLU94, PHE178, VAL179, ALA187, GLN188, MET191 and 12 more

Residues it binds most

GLU 8, VAL 8, ILE 8, MET 8, THR 8, ALA 8, LEU 8, ASN 8, PHE 8, HIS 6 (residue and the binding sites it lines).

Found with

  • HEM · Protoporphyrin IX containing Fe
  • SO4 · Sulfate ion
  • EDO · 1,2-ethanediol
  • PEG · Di(hydroxyethyl)ether
  • TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol

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