Solution structure of peptidoglycan associated lipoprotein from haemophilus influenza bound to udp-N-acetylmuramoyl-L-alanyl-D- glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

Structure

solution nmr · 2 distinct chains · 37% helix, 15% strand (DSSP).

Ligands and binding sites

• UDP · Uridine-5'-diphosphate · ligand · chains P, U
• AMU · N-acetyl-beta-muramic acid · ligand · chains U

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• P–U · 302 Ų buried · 8 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 d-amino, 1 covalent, 1 modified (D-amino acid, covalent ligand, nonstandard).

Compared structures

• 2AIZ · Solution structure of peptidoglycan associated lipoprotein from Haemophilus influenza… · the same entry in another collection · chain P against P, TM-score 1.00
• P10324 · AlphaFold monomer V2.0 prediction for peptidoglycan-associated lipoprotein (P10324) · a predicted model of the same protein · chain P against A, TM-score 0.83

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P10324
• Elsewhere: RCSB PDB 2AIZ · PDBe 2AIZ · UniProt P10324