Succinyl-aapk-trypsin acyl-enzyme at 1.28 a resolution

Structure

x-ray diffraction · 2 distinct chains · 11% helix, 36% strand (DSSP).

Ligands and binding sites

• CA · Calcium ion · metal · chains X
• SO4 · Sulfate ion · ion · chains X
• SIN · Succinic acid · additive · chains X, A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• X–A · 348 Ų buried · 14 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 disulfide, 1 covalent (disulfide, additive adduct).

Compared structures

• 2AGG · succinyl-AAPK-trypsin acyl-enzyme at 1.28 A resolution · the same entry in another collection · chain X against X, TM-score 1.00
• 1TNH · Prediction of novel serine protease inhibitors · a predicted model of the same protein · chain X against A, TM-score 1.00
• 1TNG · Prediction of novel serine protease inhibitors · a predicted model of the same protein · chain X against A, TM-score 1.00
• 1TNK · Prediction of novel serine protease inhibitors · a predicted model of the same protein · chain X against A, TM-score 1.00
• 1TNJ · Prediction of novel serine protease inhibitors · a predicted model of the same protein · chain X against A, TM-score 1.00
• 1TNL · Prediction of novel serine protease inhibitors · a predicted model of the same protein · chain X against A, TM-score 1.00
• 1TNI · Prediction of novel serine protease inhibitors · a predicted model of the same protein · chain X against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P00760
• Elsewhere: RCSB PDB 2AGG · PDBe 2AGG · UniProt P00760