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MolNFT v1 · #29618 · protein

Zinc-binding domain of ALZHEIMER'S disease amyloid beta-peptide complexed with a zinc (II) cation

1ZE9 · 16-mer from ALZHEIMER'S disease amyloid protein: “Zinc-binding domain of ALZHEIMER'S disease amyloid beta-peptide complexed with a zinc (II) cation”. Solution nmr, 3 ligands (ACE, ZN, NH2). MolNFT v1 #29618 on GenesisL1: 3D…

PDB
1ZE9
Type
protein
Length
16 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
16-mer from ALZHEIMER'S disease amyloid protein
UniProt
P05067
Ligands
ACE, ZN, NH2

Structure

solution nmr · 1 distinct chain · 19% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A16-mer from ALZHEIMER'S disease amyloid proteinprotein1619% helix, 0% strandP05067

Ligands and binding sites

  • ACE · Acetyl group · ligand · chains A
  • ZN · Zinc ion · metal · chains A
  • NH2 · Amino group · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 1 covalent (covalent ligand).

Compared structures

  • 1ZE9 · Zinc-binding domain of Alzheimer's disease amyloid beta-peptide complexed with a zinc… · the same entry in another collection · chain A against A, TM-score 1.00
  • P05067 · AlphaFold monomer V2.0 prediction for amyloid-beta precursor protein (P05067) · a predicted model of the same protein · chain A against A, TM-score 0.28

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