MolNFT v1 · #28902 · protein

Yeast cytosine deaminase triple mutant

1YSB: “Yeast cytosine deaminase triple mutant”. X-ray diffraction, 2 ligands (ZN, CA). MolNFT v1 #28902 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1YSB
Type: protein
Length: 317 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cytosine deaminase
EC: 3.5.4.1
UniProt: Q12178
Ligands: ZN, CA

Structure

x-ray diffraction · 2 distinct chains · 45% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cytosine deaminase (EC 3.5.4.1)	protein	156	46% helix, 19% strand	Q12178
B	Cytosine deaminase (EC 3.5.4.1)	protein	161	44% helix, 16% strand	Q12178

Ligands and binding sites

ZN · Zinc ion · metal · 4 copies · chains A, B
CA · Calcium ion · metal · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 1518 Å² buried · 26 hydrogen bonds · protein-protein

Compared structures

1YSB · Yeast Cytosine Deaminase Triple Mutant · the same entry in another collection · chain A against A, TM-score 1.00
Q12178 · AlphaFold monomer V2.0 prediction for cytosine deaminase (Q12178) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q12178
Elsewhere: RCSB PDB 1YSB · PDBe 1YSB · UniProt Q12178

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