MolNFT v1 · #25767 · protein

Crystal structure of a proteolyzed form of pancreatic lipase related protein 2 from horse

1W52: “Crystal structure of a proteolyzed form of pancreatic lipase related protein 2 from horse”. X-ray diffraction, 2 ligands (DDQ, CA), 2 pockets (best druggability 0.57). MolNFT v1 #25767 on GenesisL1: 3D structure, binding sites and…

PDB: 1W52
Type: protein
Length: 448 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pancreatic lipase related protein 2
UniProt: Q95KP4
Ligands: DDQ, CA
Pockets: 2 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 24% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Pancreatic lipase related protein 2	protein	448	24% helix, 20% strand	Q95KP4

Ligands and binding sites

DDQ · Decylamine-N,N-dimethyl-N-oxide · ligand · 2 copies · chains X
CA · Calcium ion · metal · 2 copies · chains X

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	156	0.57	0.81	23	DDQ
2	53	0.28	0.74	16	empty

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

1W52 · Crystal structure of a proteolyzed form of pancreatic lipase related protein 2 from horse · the same entry in another collection · chain X against X, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q95KP4
Elsewhere: RCSB PDB 1W52 · PDBe 1W52 · UniProt Q95KP4

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