MolNFT v1 · #25424 · protein
Human vascular endothelial growth factor receptor 2 (kdr) kinase domain
1VR2 · Protein (vascular endothelial growth factor receptor kinase): “Human vascular endothelial growth factor receptor 2 (kdr) kinase domain”. X-ray diffraction, 1 pocket (best druggability 0.52). MolNFT v1 #25424 on GenesisL1: 3D…
- PDB
- 1VR2
- Type
- protein
- Length
- 275 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein (vascular endothelial growth factor receptor kinase)
- EC
- 2.7.1.112
- UniProt
- P35968
- Pockets
- 1 · best druggability 0.52
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein (vascular endothelial growth factor receptor kinase) (EC 2.7.1.112) | protein | 275 | 41% helix, 17% strand | P35968 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 239 | 0.52 | 0.75 | 30 | empty |
Compared structures
- 1VR2 · Human vascular endothelial growth factor receptor 2 (kdr) kinase domain · the same entry in another collection · chain A against A, TM-score 1.00
- P35968 · AlphaFold monomer V2.0 prediction for vascular endothelial growth factor receptor 2… · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35968
- Elsewhere: RCSB PDB 1VR2 · PDBe 1VR2 · UniProt P35968
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.