MolNFT v1 · #24227 · protein
X-ray structure of the RNase domain of the yeast POP2 protein
1UOC: “X-ray structure of the RNase domain of the yeast POP2 protein”. X-ray diffraction, 2 ligands (CA, XE), 6 pockets (best druggability 0.41). MolNFT v1 #24227 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1UOC
- Type
- protein
- Length
- 517 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- POP2
- UniProt
- P39008
- Ligands
- CA, XE
- Pockets
- 6 · best druggability 0.41
Structure
x-ray diffraction · 2 distinct chains · 45% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | POP2 | protein | 263 | 44% helix, 14% strand | P39008 |
| B | POP2 | protein | 254 | 47% helix, 15% strand | P39008 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 136 | 0.41 | 0.74 | 21 | empty |
| 2 | 123 | 0.39 | 0.74 | 20 | empty |
| 3 | 103 | 0.35 | 0.74 | 20 | empty |
| 4 | 80 | 0.34 | 0.75 | 19 | empty |
| 5 | 64 | 0.28 | 0.73 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 454 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P39008
- Elsewhere: RCSB PDB 1UOC · PDBe 1UOC · UniProt P39008
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