MolNFT v1 · #21819 · protein

Studies on an artificial trypsin inhibitor peptide derived from the mung bean inhibitor

1SMF: “Studies on an artificial trypsin inhibitor peptide derived from the mung bean inhibitor”. X-ray diffraction, 1 ligand (CA). MolNFT v1 #21819 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1SMF
Type: protein
Length: 232 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Trypsin; Bowman-birk type trypsin inhibitor
EC: 3.4.21.4
UniProt: P00760, P01062
Ligands: CA

Structure

x-ray diffraction · 2 distinct chains · 10% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
E	Trypsin (EC 3.4.21.4)	protein	223	11% helix, 36% strand	P00760
I	Bowman-birk type trypsin inhibitor	protein	9	0% helix, 11% strand	P01062

Ligands and binding sites

CA · Calcium ion · metal · chains E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

E–I · 505 Å² buried · 16 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 7 disulfide (disulfide).

Compared structures

1SMF · Studies on an artificial trypsin inhibitor peptide derived from the mung bean inhibitor · the same entry in another collection · chain E against E, TM-score 1.00
P01062 · AlphaFold monomer V2.0 prediction for bowman-birk type trypsin inhibitor (P01062) · a predicted model of the same protein · chain I against A, TM-score 0.82

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00760
Every structure of UniProt P01062
Elsewhere: RCSB PDB 1SMF · PDBe 1SMF · UniProt P00760 · UniProt P01062

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.