MolNFT v1 · #19764 · protein
The 1.65 ångström structure of calmodulin RS20 peptide complex
1QTX · Protein (calmodulin): “The 1.65 ångström structure of calmodulin RS20 peptide complex”. X-ray diffraction, 2 ligands (CA, NH2), 3 pockets (best druggability 0.41). MolNFT v1 #19764 on GenesisL1: 3D structure, binding sites and…
- PDB
- 1QTX
- Type
- protein
- Length
- 168 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein (calmodulin); Protein (RS20)
- UniProt
- P11799
- Ligands
- CA, NH2
- Pockets
- 3 · best druggability 0.41
Structure
x-ray diffraction · 2 distinct chains · 60% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein (calmodulin) | protein | 148 | 57% helix, 5% strand | — |
| B | Protein (RS20) | protein | 20 | 80% helix, 0% strand | P11799 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 130 | 0.41 | 0.75 | 20 | empty |
| 2 | 91 | 0.41 | 0.78 | 22 | empty |
| 3 | 50 | 0.29 | 0.76 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 1618 Ų buried · 23 hydrogen bonds · protein-protein
Compared structures
- 1QTX · The 1.65 ångström structure of calmodulin RS20 peptide complex · the same entry in another collection · chain A against A, TM-score 1.00
- P11799 · AlphaFold monomer V2.0 prediction for myosin light chain kinase, smooth muscle (P11799) · a predicted model of the same protein · chain B against A, TM-score 0.61
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P11799
- Elsewhere: RCSB PDB 1QTX · PDBe 1QTX · UniProt P11799
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.