MolNFT v1 · #255473 · protein
AlphaFold monomer V2.0 prediction for myosin light chain kinase, smooth muscle (P11799)
P11799: “AlphaFold monomer V2.0 prediction for myosin light chain kinase, smooth muscle (P11799)”. 14 pockets (best druggability 0.71). MolNFT v1 #255473 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P11799
- Type
- protein
- Length
- 1,906 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xbb2F1C7CB3A1eeFAc24fCa72cc627162D5413FD7
- Molecule
- Myosin light chain kinase, smooth muscle
- UniProt
- P11799
- Pockets
- 14 · best druggability 0.71
Structure
1 distinct chain · 9% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Myosin light chain kinase, smooth muscle | protein | 1906 | 9% helix, 34% strand | P11799 |
Pockets
14 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 617 | 0.71 | 0.79 | 62 | empty |
| 2 | 479 | 0.59 | 0.74 | 54 | empty |
| 3 | 204 | 0.45 | 0.73 | 28 | empty |
| 4 | 208 | 0.44 | 0.73 | 25 | empty |
| 5 | 155 | 0.44 | 0.75 | 23 | empty |
Compared structures
- 3O77 · The structure of CA2+ sensor (case-16) · an experimental structure of the same protein · chain A against A, TM-score 0.09
- 3O77 · The structure of Ca2+ Sensor (Case-16) · an experimental structure of the same protein · chain A against A, TM-score 0.09
- 3O78 · The structure of CA2+ sensor (case-12) · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 3O78 · The structure of Ca2+ Sensor (Case-12) · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 3EVU · Crystal structure of Calcium bound dimeric GCAMP2 · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 3EVU · Crystal structure of calcium bound dimeric GCAMP2 · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 1CDL · Target enzyme recognition by calmodulin: 2.4 ångströms structure of a calmodulin-peptide… · an experimental structure of the same protein · chain A against G, TM-score 0.01
- 1CDL · Target enzyme recognition by calmodulin: 2.4 ångströms structure of a calmodulin-peptide… · an experimental structure of the same protein · chain A against G, TM-score 0.01
- 1QTX · The 1.65 ångström structure of calmodulin RS20 peptide complex · an experimental structure of the same protein · chain A against B, TM-score 0.01
- 1QTX · The 1.65 ångström structure of calmodulin RS20 peptide complex · an experimental structure of the same protein · chain A against B, TM-score 0.01
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P11799
- Elsewhere: UniProt P11799 · AlphaFold DB P11799
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