MolNFT v1 · #191341 · protein
CEREBLON~DDB1 bound to pomalidomide
8D81: “CEREBLON~DDB1 bound to pomalidomide”. Electron microscopy, 2 ligands (Y70, ZN). MolNFT v1 #191341 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 8D81
- Type
- protein
- Length
- 1,198 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q16531, Q96SW2
- Ligands
- Y70, ZN
Structure
electron microscopy · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 817 | — | Q16531 |
| B | — | protein | 381 | — | Q96SW2 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 8D81 · Cereblon~DDB1 bound to Pomalidomide · the same entry in another collection · chain A against A, TM-score 1.00
- Q16531 · AlphaFold monomer V2.0 prediction for DNA damage-binding protein 1 (Q16531) · a predicted model of the same protein · chain A against A, TM-score 0.98
- Q96SW2 · AlphaFold monomer V2.0 prediction for protein cereblon (Q96SW2) · a predicted model of the same protein · chain B against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q16531
- Every structure of UniProt Q96SW2
- Elsewhere: RCSB PDB 8D81 · PDBe 8D81 · UniProt Q16531 · UniProt Q96SW2
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