MolNFT v1 · #191301 · protein

HBEST1 CA2+-bound partially open aperture state

8D1L: “HBEST1 CA2+-bound partially open aperture state”. Electron microscopy, 3 ligands (MC3, CA, CL). MolNFT v1 #191301 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 8D1L
Type: protein
Length: 1,880 residues
Chains: 5
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: O76090
Ligands: MC3, CA, CL

Structure

electron microscopy · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B, C, A, D, E	—	protein	376	—	O76090

Ligands and binding sites

MC3 · 1,2-dimyristoyl-rac-glycero-3-phosphocholine · ligand · 40 copies · chains B, C, D, A, E
CA · Calcium ion · metal · 5 copies · chains B, A, C, E, D
CL · Chloride ion · ion · chains B, C, A, D, E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

8D1L · hBest1 Ca2+-bound partially open aperture state · the same entry in another collection · chain E against E, TM-score 1.00
O76090 · AlphaFold monomer V2.0 prediction for bestrophin-1 (O76090) · a predicted model of the same protein · chain B against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O76090
Elsewhere: RCSB PDB 8D1L · PDBe 8D1L · UniProt O76090

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