MolNFT v1 · #191121 · protein
PFS48/45 bound to monoclonal antibodies 10D8 and 85RF45.1
7ZXF: “PFS48/45 bound to monoclonal antibodies 10D8 and 85RF45.1”. X-ray diffraction, 3 ligands (NAG, BMA, MAN). MolNFT v1 #191121 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7ZXF
- Type
- protein
- Length
- 1,190 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8I6T1
- Ligands
- NAG, BMA, MAN
Structure
x-ray diffraction · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 337 | — | Q8I6T1 |
| B | — | protein | 206 | — | — |
| C | — | protein | 216 | — | — |
| D | — | protein | 214 | — | — |
| E | — | protein | 217 | — | — |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains A, E
- BMA · beta-D-mannopyranose · sugar · 2 copies · chains E
- MAN · alpha-D-mannopyranose · sugar · 2 copies
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7ZXF · Pfs48/45 bound to monoclonal antibodies 10D8 and 85RF45.1 · the same entry in another collection · chain A against A, TM-score 1.00
- Q8I6T1 · AlphaFold monomer V2.0 prediction for gametocyte surface protein P45/48 (Q8I6T1) · a predicted model of the same protein · chain A against A, TM-score 0.70
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8I6T1
- Elsewhere: RCSB PDB 7ZXF · PDBe 7ZXF · UniProt Q8I6T1
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