MolNFT v1 · #190923 · protein

PI3KC2A core in complex with PITCOIN2

7Z74: “PI3KC2A core in complex with PITCOIN2”. X-ray diffraction, 1 ligand (IKC). MolNFT v1 #190923 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7Z74
Type: protein
Length: 822 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q61194
Ligands: IKC

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	822	—	Q61194

Ligands and binding sites

IKC · ~{N}-[4-(3-hydroxyphenyl)-1,3-thiazol-2-yl]-2-[4-oxidanylidene-3-(2-phenylethyl)pteridin-2-yl]sulfanyl-ethanamide · ligand · chains A
EDO · 1,2-ethanediol · additive · 5 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7Z74 · PI3KC2a core in complex with PITCOIN2 · the same entry in another collection · chain A against A, TM-score 1.00
Q61194 · AlphaFold monomer V2.0 prediction for phosphatidylinositol 4-phosphate 3-kinase C2… · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q61194
Elsewhere: RCSB PDB 7Z74 · PDBe 7Z74 · UniProt Q61194

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