MolNFT v1 · #190644 · protein + DNA

Cryo-EM structure of the histone methyltransferase SET8 bound to H4K20ECX-nucleosome

7XPX: “Cryo-EM structure of the histone methyltransferase SET8 bound to H4K20ECX-nucleosome”. Electron microscopy. MolNFT v1 #190644 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7XPX
Type: protein + DNA
Length: 1,225 residues
Chains: 11
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: A0A310TTQ1, Q6AZJ8, P02281, Q9NQR1

Structure

electron microscopy · 11 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	99	—	A0A310TTQ1
B	—	protein	86	—	—
C	—	protein	108	—	Q6AZJ8
D	—	protein	96	—	P02281
E	—	protein	98	—	A0A310TTQ1
F	—	protein	79	—	—
G	—	protein	105	—	Q6AZJ8
H	—	protein	96	—	P02281
I	—	dna	145	—	—
J	—	dna	145	—	—
K	—	protein	168	—	Q9NQR1

Compared structures

7XPX · Cryo-EM structure of the histone methyltransferase SET8 bound to H4K20Ecx-nucleosome · the same entry in another collection · chain J against J, TM-score 1.00
Q9NQR1 · AlphaFold monomer V2.0 prediction for N-lysine methyltransferase KMT5A (Q9NQR1) · a predicted model of the same protein · chain K against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A310TTQ1
Every structure of UniProt Q6AZJ8
Every structure of UniProt P02281
Every structure of UniProt Q9NQR1
Elsewhere: RCSB PDB 7XPX · PDBe 7XPX · UniProt A0A310TTQ1 · UniProt Q6AZJ8 · UniProt P02281 · UniProt Q9NQR1

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