MolNFT v1 · #190185 · protein
The curved structure of MPIEZO1 in lipid bilayer
7WLT: “The curved structure of MPIEZO1 in lipid bilayer”. Electron microscopy, 2 ligands (PLX, PEE). MolNFT v1 #190185 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7WLT
- Type
- protein
- Length
- 4,062 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- E2JF22
- Ligands
- PLX, PEE
Structure
electron microscopy · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C, E | — | protein | 1354 | — | E2JF22 |
Ligands and binding sites
- PLX · (9R,11S)-9-({[(1S)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol · ligand · 21 copies · chains A, C, E
- PEE · 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine · ligand · 3 copies · chains A, E, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7WLT · the Curved Structure of mPIEZO1 in Lipid Bilayer · the same entry in another collection · chain C against C, TM-score 1.00
- E2JF22 · AlphaFold monomer V2.0 prediction for piezo-type mechanosensitive ion channel component 1… · a predicted model of the same protein · chain A against A, TM-score 0.81
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E2JF22
- Elsewhere: RCSB PDB 7WLT · PDBe 7WLT · UniProt E2JF22
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