MolNFT v1 · #190059 · protein
Human TRPC5 channel in complex with riluzole
7WDB: “Human TRPC5 channel in complex with riluzole”. Electron microscopy, 7 ligands (POV, Y01, 657). MolNFT v1 #190059 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7WDB
- Type
- protein
- Length
- 2,660 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9UL62
- Ligands
- POV, Y01, 657, PTY, 7OC, ZN, CA
Structure
electron microscopy · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | — | protein | 665 | — | Q9UL62 |
Ligands and binding sites
- POV · (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate · ligand · 4 copies · chains A, B, C, D
- Y01 · Cholesterol hemisuccinate · ligand · 4 copies · chains A, D, B, C
- 657 · 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine · ligand · 4 copies · chains A, B, C, D
- PTY · Phosphatidylethanolamine · ligand · 4 copies · chains A, D, B, C
- 7OC · [3-[(~{E})-octadec-10-enoyl]oxy-2-oxidanyl-propyl] (~{E})-octadec-10-enoate · ligand · 4 copies · chains A, D, B, C
- ZN · Zinc ion · metal · 4 copies · chains A, B, C, D
- CA · Calcium ion · metal · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UL62
- Elsewhere: RCSB PDB 7WDB · PDBe 7WDB · UniProt Q9UL62
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