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MolNFT v1 · #18990 · protein

Solution structure of T-cell surface glycoprotein CD4 and proto- oncogene tyrosine-protein kinase lck fragments

1Q68: “Solution structure of T-cell surface glycoprotein CD4 and proto- oncogene tyrosine-protein kinase lck…”. Solution nmr, 1 ligand (ZN). MolNFT v1 #18990 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
1Q68
Type
protein
Length
67 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
T-cell surface glycoprotein CD4; Proto-oncogene tyrosine-protein kinase lck
UniProt
P01730, P06239
Ligands
ZN

Structure

solution nmr · 2 distinct chains · 21% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AT-cell surface glycoprotein CD4protein3826% helix, 0% strandP01730
BProto-oncogene tyrosine-protein kinase lckprotein2914% helix, 0% strandP06239

Ligands and binding sites

  • ZN · Zinc ion · metal · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 502 Ų buried · 1 hydrogen bond · protein-protein

Compared structures

  • 1Q68 · Solution structure of T-cell surface glycoprotein CD4 and Proto-oncogene tyrosine-protein… · the same entry in another collection · chain A against A, TM-score 1.00
  • P01730 · AlphaFold monomer V2.0 prediction for T-cell surface glycoprotein CD4 (P01730) · a predicted model of the same protein · chain A against A, TM-score 0.37
  • P06239 · AlphaFold monomer V2.0 prediction for tyrosine-protein kinase lck (P06239) · a predicted model of the same protein · chain B against A, TM-score 0.34

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