MolNFT v1 · #189884 · protein
The closed conformation of the sigma-1 receptor from xenopus laevis complexed with PRE084
7W2C: “The closed conformation of the sigma-1 receptor from xenopus laevis complexed with PRE084”. X-ray diffraction, 2 ligands (E84, AU). MolNFT v1 #189884 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7W2C
- Type
- protein
- Length
- 2,590 residues
- Chains
- 12
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q6DCU6
- Ligands
- E84, AU
Structure
x-ray diffraction · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, E, B, F, H, I, K, L | — | protein | 215 | — | Q6DCU6 |
| C | — | protein | 217 | — | Q6DCU6 |
| D | — | protein | 219 | — | Q6DCU6 |
| G | — | protein | 214 | — | Q6DCU6 |
| J | — | protein | 220 | — | Q6DCU6 |
Ligands and binding sites
- E84 · 2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate · ligand · 12 copies · chains A, C, E, B, D, F, G, H, I, J, K, L
- AU · Gold ion · metal · 24 copies · chains A, C, E, B, D, I, F, G, H, J, K, L
- BOG · octyl beta-D-glucopyranoside · additive · 3 copies · chains A, E, C, B, D, H, J, L
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7W2C · The closed conformation of the sigma-1 receptor from Xenopus laevis complexed with PRE084 · the same entry in another collection · chain L against L, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6DCU6
- Elsewhere: RCSB PDB 7W2C · PDBe 7W2C · UniProt Q6DCU6
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