Ligand · E84
E84 · 2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate
E84, 2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate (C19 H27 N O3, 317.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds…
- Component
- E84
- Formula
- C19 H27 N O3
- Class
- ligand
- Structures
- 4
- PDB entries
- 3
Binding sites
E84 in 4 structures; the first of them:
- 7W2F · An open-like conformation of the sigma-1 receptor from Xenopus laevis complexed with… · E84 A301 · binds VAL81, TRP86, MET90, TYR100, LEU102, PHE104, SER114, TYR117 and 11 more
- 7W2C · The closed conformation of the sigma-1 receptor from xenopus laevis complexed with PRE084 · E84 A403 · binds MET90, TYR100, LEU102, PHE104, TYR117, ILE121, ASP123, TRP161 and 4 more
- 7W2F · An open-like conformation of the sigma-1 receptor from xenopus laevis complexed with… · E84 A301 · binds TRP86, MET90, TYR100, LEU102, PHE104, TYR117, ILE121, ASP123 and 5 more
- 7W2G · An open-like conformation of the sigma-1 receptor from xenopus laevis complexed with… · E84 A301 · binds VAL81, TRP86, MET90, TYR100, LEU102, PHE104, TYR117, ILE121 and 6 more
Residues it binds most
TYR 48, PHE 48, TRP 44, THR 46, LEU 41, GLU 48, ALA 44, ILE 44, ASP 41, MET 37 (residue and the binding sites it lines).
Found with
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