MolNFT v1 · #189716 · protein
Cryo-EM structure of a human ATP11C-CDC50A flippase reconstituted in the nanodisc in ptdser-occluded E2-pi state.
7VSG: “Cryo-EM structure of a human ATP11C-CDC50A flippase reconstituted in the nanodisc in ptdser-occluded E2-pi…”. Electron microscopy, 3 ligands (17F, NAG, MAN). MolNFT v1 #189716 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 7VSG
- Type
- protein
- Length
- 1,139 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8NB49, Q9NV96
- Ligands
- 17F, NAG, MAN
Structure
electron microscopy · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 815 | — | Q8NB49 |
| B | — | protein | 324 | — | Q9NV96 |
Ligands and binding sites
- 17F · O-[(S)-({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine · ligand · chains A
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains A, B
- MAN · alpha-D-mannopyranose · sugar · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7VSG · Cryo-EM structure of a human ATP11C-CDC50A flippase reconstituted in the Nanodisc in… · the same entry in another collection · chain B against B, TM-score 1.00
- Q9NV96 · AlphaFold monomer V2.0 prediction for cell cycle control protein 50A (Q9NV96) · a predicted model of the same protein · chain B against A, TM-score 0.93
- Q8NB49 · AlphaFold monomer V2.0 prediction for phospholipid-transporting ATPase ig (Q8NB49) · a predicted model of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8NB49
- Every structure of UniProt Q9NV96
- Elsewhere: RCSB PDB 7VSG · PDBe 7VSG · UniProt Q8NB49 · UniProt Q9NV96
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