UniProt Q8NB49
Phospholipid-transporting ATPase IG (Q8NB49)
Phospholipid-transporting ATPase IG (UniProt Q8NB49), EC 7.6.2.1: 6 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q8NB49
- Protein
- Phospholipid-transporting ATPase IG
- EC
- 7.6.2.1
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 15 · 1 record with a druggable one
Structures
7 records of Q8NB49 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6LKN | Crystal structure of ATP11C-CDC50A in PtdSer-bound E2P state | x-ray diffraction | A, E, I, M | MG | — |
| 6LKN | Crystal structure of ATP11C-CDC50A in ptdser-bound E2P state | x-ray diffraction | A, E, I, M | MG | — |
| 7VSG | Cryo-EM structure of a human ATP11C-CDC50A flippase reconstituted in the Nanodisc in… | electron microscopy | A | NAG, 17F | 15 (best 0.76) |
| 7VSG | Cryo-EM structure of a human ATP11C-CDC50A flippase reconstituted in the nanodisc in… | electron microscopy | A | NAG, 17F | — |
| 7VSH | Cryo-EM structure of a human ATP11C-CDC50A flippase reconstituted in the Nanodisc in E1P state. | electron microscopy | A | NAG, MG, ALF, 17F | — |
| 7VSH | Cryo-EM structure of a human ATP11C-CDC50A flippase reconstituted in the nanodisc in E1P state. | electron microscopy | A | NAG, MG, ALF, 17F | — |
| Q8NB49 | AlphaFold monomer V2.0 prediction for phospholipid-transporting ATPase ig (Q8NB49) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6LKN chain A against the predicted model Q8NB49: TM-score 0.93, RMSD 2.79 Å
- 6LKN chain A against the predicted model Q8NB49: TM-score 0.93, RMSD 2.79 Å
- 7VSG chain A against the predicted model Q8NB49: TM-score 0.92, RMSD 2.93 Å
- 7VSG chain A against the predicted model Q8NB49: TM-score 0.92, RMSD 2.93 Å
- 6LKN chain E against the predicted model Q8NB49: TM-score 0.92, RMSD 3.10 Å
- 6LKN chain E against the predicted model Q8NB49: TM-score 0.92, RMSD 3.10 Å
- 6LKN chain I against the predicted model Q8NB49: TM-score 0.91, RMSD 2.94 Å
- 6LKN chain I against the predicted model Q8NB49: TM-score 0.91, RMSD 2.94 Å
- 6LKN chain M against the predicted model Q8NB49: TM-score 0.91, RMSD 3.23 Å
- 6LKN chain M against the predicted model Q8NB49: TM-score 0.91, RMSD 3.23 Å
Elsewhere
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