MolNFT v1 · #188978 · protein

Integrin ALPHAM/BETA2 ectodomain in complex with adenylate cyclase toxin RTX751 and M1F5 Fab

7USL: “Integrin ALPHAM/BETA2 ectodomain in complex with adenylate cyclase toxin RTX751 and M1F5 Fab”. Electron microscopy, 3 ligands (NAG, FUC, CA). MolNFT v1 #188978 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7USL
Type: protein
Length: 2,464 residues
Chains: 5
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P11215, A0A494C0X7, A5JW88
Ligands: NAG, FUC, CA

Structure

electron microscopy · 5 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	856	—	P11215
B	—	protein	673	—	A0A494C0X7
C	—	protein	715	—	A5JW88
H	—	protein	114	—	—
L	—	protein	106	—	—

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 15 copies · chains A, C, B
FUC · alpha-L-fucopyranose · sugar · chains A, C
CA · Calcium ion · metal · 33 copies · chains A, B, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7USL · Integrin alphaM/beta2 ectodomain in complex with adenylate cyclase toxin RTX751 and M1F5… · the same entry in another collection · chain A against A, TM-score 1.00
P11215 · AlphaFold monomer V2.0 prediction for integrin alpha-M (P11215) · a predicted model of the same protein · chain A against A, TM-score 0.66

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P11215
Every structure of UniProt A0A494C0X7
Every structure of UniProt A5JW88
Elsewhere: RCSB PDB 7USL · PDBe 7USL · UniProt P11215 · UniProt A0A494C0X7 · UniProt A5JW88

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