MolNFT v1 · #188352 · protein
Complex gnnn of AMPA-subtype iglur GLUA2 in complex with auxiliary subunit GAMMA2 (stargazin) at low glutamate concentration (20 um) in the presence of cyclothiazide (100 um)
7TNK: “Complex gnnn of AMPA-subtype iglur GLUA2 in complex with auxiliary subunit GAMMA2 (stargazin) at low…”. Electron microscopy, 1 ligand (CYZ). MolNFT v1 #188352 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7TNK
- Type
- protein
- Length
- 2,419 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P19491, Q8VHX0
- Ligands
- CYZ
Structure
electron microscopy · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 616 | — | P19491, Q8VHX0 |
| B, D | — | protein | 602 | — | P19491, Q8VHX0 |
| C | — | protein | 599 | — | P19491, Q8VHX0 |
Ligands and binding sites
- CYZ · Cyclothiazide · ligand · 4 copies · chains A, D, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7TNK · Complex GNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2… · the same entry in another collection · chain C against C, TM-score 1.00
- P19491 · AlphaFold monomer V2.0 prediction for glutamate receptor 2 (P19491) · a predicted model of the same protein · chain D against A, TM-score 0.64
- Q8VHX0 · AlphaFold monomer V2.0 prediction for voltage-dependent calcium channel gamma-3 subunit… · a predicted model of the same protein · chain A against A, TM-score 0.31
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P19491
- Every structure of UniProt Q8VHX0
- Elsewhere: RCSB PDB 7TNK · PDBe 7TNK · UniProt P19491 · UniProt Q8VHX0
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