Ternary complex of fixed-arm trx-3OST5 (I299E) with 8MER-2 octasaccharide substrate and co-factor product pap

Structure

x-ray diffraction · 1 distinct chain.

Ligands and binding sites

• A3P · Adenosine-3'-5'-diphosphate · ligand · chains A
• SGN · 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose · sugar · 3 copies · chains A
• BDP · beta-D-glucopyranuronic acid · sugar · 2 copies · chains A
• IDS · 2-O-sulfo-alpha-L-idopyranuronic acid · sugar · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7SCE · Ternary complex of fixed-arm Trx-3ost5 (I299E) with 8mer-2 octasaccharide substrate and… · the same entry in another collection · chain A against A, TM-score 1.00
• Q8IZT8 · AlphaFold monomer V2.0 prediction for heparan sulfate glucosamine 3-O-sulfotransferase 5… · a predicted model of the same protein · chain A against A, TM-score 0.71

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P0AA25
• Every structure of UniProt Q8IZT8
• Elsewhere: RCSB PDB 7SCE · PDBe 7SCE · UniProt P0AA25 · UniProt Q8IZT8