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MolNFT v1 · #186364 · protein + DNA

Human DNA polymerase beta crosslinked complex, 60 S ca to mn exchange

7RBM: “Human DNA polymerase beta crosslinked complex, 60 S ca to mn exchange”. X-ray diffraction, 3 ligands (QPJ, PPV, MN). MolNFT v1 #186364 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7RBM
Type
protein + DNA
Length
357 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P06746
Ligands
QPJ, PPV, MN

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein325—P06746
D—dna5——
P—dna11——
T—dna16——

Ligands and binding sites

  • QPJ · 2-deoxy-3,5-di-O-phosphono-D-erythro-pentitol · ligand · chains A, D
  • PPV · Pyrophosphate · ligand · chains A, P
  • MN · Manganese (II) ion · metal · 11 copies · chains A, P, D, T

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7RBM · Human DNA polymerase beta crosslinked complex, 60 s Ca to Mn exchange · the same entry in another collection · chain A against A, TM-score 1.00
  • P06746 · AlphaFold monomer V2.0 prediction for DNA polymerase beta (P06746) · a predicted model of the same protein · chain A against A, TM-score 0.93

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