GL1X · GenesisL1 explorer

MolNFT v1 · #185977 · protein

26S proteasome wt-UBP6-ubvs complex in the si state (atpases, RPN1, UBP6, and ubvs)

7QO4: “26S proteasome wt-UBP6-ubvs complex in the si state (atpases, RPN1, UBP6, and ubvs)”. Electron microscopy, 3 ligands (ATP, ADP, MG). MolNFT v1 #185977 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7QO4
Type
protein
Length
3,737 residues
Chains
9
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P38764, A0A6A5PV22, A0A6A5Q382, A0A6A5PYF7, A0A6A5Q8D3, A0A6A5Q672, A0A6A5PWS2, A0A6A5PXS0, J3QS39
Ligands
ATP, ADP, MG

Structure

electron microscopy · 9 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
Z—protein906—P38764
H—protein391—A0A6A5PV22
I—protein384—A0A6A5Q382
K—protein394—A0A6A5PYF7
L—protein388—A0A6A5Q8D3
M—protein421—A0A6A5Q672
J—protein405—A0A6A5PWS2
8—protein372—A0A6A5PXS0
9—protein76—J3QS39

Ligands and binding sites

  • ATP · Adenosine-5'-triphosphate · ligand · 5 copies · chains H, I, J, K, L, M
  • ADP · Adenosine-5'-diphosphate · ligand · chains J
  • MG · Magnesium ion · metal · 6 copies · chains H, J, K, L, M

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7QO4 · 26S proteasome WT-Ubp6-UbVS complex in the si state (ATPases, Rpn1, Ubp6, and UbVS) · the same entry in another collection · chain 9 against 9, TM-score 1.00
  • P38764 · AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN1 (P38764) · a predicted model of the same protein · chain Z against A, TM-score 0.83

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