MolNFT v1 · #185750 · protein
Hisf-C9A-D11E-V33A_L50H_I52H mutant in complex with NI(II) from T. maritima
7QC9 · Imidazole glycerol phosphate synthase subunit hisf: “Hisf-C9A-D11E-V33A_L50H_I52H mutant in complex with NI(II) from T. maritima”. X-ray diffraction, 2 ligands (NI, SO4), 1 pocket (best druggability 0.69). MolNFT v1 #185750 on…
- PDB
- 7QC9
- Type
- protein
- Length
- 242 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Imidazole glycerol phosphate synthase subunit hisf
- EC
- 4.3.2.10
- UniProt
- Q9X0C6
- Ligands
- NI, SO4
- Pockets
- 1 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Imidazole glycerol phosphate synthase subunit hisf (EC 4.3.2.10) | protein | 242 | 41% helix, 26% strand | Q9X0C6 |
Ligands and binding sites
- NI · Nickel (II) ion · metal · chains A
- SO4 · Sulfate ion · ion · chains A
- EDO · 1,2-ethanediol · additive · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 419 | 0.69 | 0.81 | 46 | SO4 |
Compared structures
- 7QC9 · HisF-C9A-D11E-V33A_L50H_I52H mutant in complex with Ni(II) from T. maritima · the same entry in another collection · chain A against A, TM-score 1.00
- Q9X0C6 · AlphaFold monomer V2.0 prediction for imidazole glycerol phosphate synthase subunit hisf… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9X0C6
- Elsewhere: RCSB PDB 7QC9 · PDBe 7QC9 · UniProt Q9X0C6
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