MolNFT v1 · #184843 · protein
Crystal structure of monoamine oxidase B in complex with inhibitor (+)-2
7P4H: “Crystal structure of monoamine oxidase B in complex with inhibitor (+)-2”. X-ray diffraction, 3 ligands (FAD, 5IH, C15). MolNFT v1 #184843 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7P4H
- Type
- protein
- Length
- 993 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P27338
- Ligands
- FAD, 5IH, C15
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 499 | — | P27338 |
| B | — | protein | 494 | — | P27338 |
Ligands and binding sites
- FAD · Flavin-adenine dinucleotide · ligand · 2 copies · chains A, B
- 5IH · 3,4-dimethyl-7-[[(3~{S})-piperidin-3-yl]methoxy]chromen-2-one · ligand · 2 copies · chains A, B
- C15 · N-dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7P4H · Crystal Structure of Monoamine Oxidase B in complex with inhibitor (+)-2 · the same entry in another collection · chain B against B, TM-score 1.00
- P27338 · AlphaFold monomer V2.0 prediction for amine oxidase [flavin- containing] B (P27338) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P27338
- Elsewhere: RCSB PDB 7P4H · PDBe 7P4H · UniProt P27338
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