MolNFT v1 · #184705 · protein
Structure of human galactokinase 1 bound with azepan-1-YL(2,6- DIFLUOROPHENYL)METHANONE
7OZX: “Structure of human galactokinase 1 bound with azepan-1-YL(2,6- DIFLUOROPHENYL)METHANONE”. X-ray diffraction, 3 ligands (HFK, WLJ, GAL). MolNFT v1 #184705 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7OZX
- Type
- protein
- Length
- 1,534 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P51570
- Ligands
- HFK, WLJ, GAL
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 390 | — | P51570 |
| B, C | — | protein | 391 | — | P51570 |
| D | — | protein | 362 | — | P51570 |
Ligands and binding sites
- HFK · 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one · ligand · 3 copies · chains A, B, C
- WLJ · (azepan-1-yl)(2,6-difluorophenyl)methanone · ligand · 2 copies · chains B, C
- GAL · beta-D-galactopyranose · sugar · 3 copies · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7OZX · Structure of human galactokinase 1 bound with azepan-1-yl(2,6-difluorophenyl)metha · the same entry in another collection · chain D against D, TM-score 1.00
- P51570 · AlphaFold monomer V2.0 prediction for galactokinase (P51570) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P51570
- Elsewhere: RCSB PDB 7OZX · PDBe 7OZX · UniProt P51570
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.