MolNFT v1 · #184597 · protein
Human soluble adenylyl cyclase in complex with the inhibitor TDI10229
7OVD: “Human soluble adenylyl cyclase in complex with the inhibitor TDI10229”. X-ray diffraction, 1 ligand (1S2). MolNFT v1 #184597 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7OVD
- Type
- protein
- Length
- 449 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q96PN6
- Ligands
- 1S2
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 449 | — | Q96PN6 |
Ligands and binding sites
- 1S2 · 4-chloranyl-6-[1,5-dimethyl-4-(phenylmethyl)pyrazol-3-yl]pyrimidin-2-amine · ligand · chains A
- EDO · 1,2-ethanediol · additive · 6 copies · chains A
- ACT · Acetate ion · additive · 4 copies · chains A
- DMS · Dimethyl sulfoxide · additive · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7OVD · Human soluble adenylyl cyclase in complex with the inhibitor TDI10229 · the same entry in another collection · chain A against A, TM-score 1.00
- Q96PN6 · AlphaFold monomer V2.0 prediction for adenylate cyclase type 10 (Q96PN6) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96PN6
- Elsewhere: RCSB PDB 7OVD · PDBe 7OVD · UniProt Q96PN6
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