GL1X · GenesisL1 explorer

Ligand · 1S2

1S2 · 4-chloranyl-6-[1,5-dimethyl-4-(phenylmethyl)pyrazol-3-yl]pyrimidin-2-amine

1S2, 4-chloranyl-6-[1,5-dimethyl-4-(phenylmethyl)pyrazol-3-yl]pyrimidin-2-amine (C16 H16 Cl N5, 313.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
1S2
Formula
C16 H16 Cl N5
Class
ligand
Structures
2
PDB entries
1

Binding sites

1S2 in 2 structures; the first of them:

  • 7OVD · Human soluble adenylyl cyclase in complex with the inhibitor TDI10229 · 1S2 A501 · binds PHE45, LEU94, LYS95, PHE96, ALA97, ASP99, ALA100, LEU101 and 10 more
  • 7OVD · Human soluble adenylyl cyclase in complex with the inhibitor TDI10229 · 1S2 A501 · binds PHE45, LYS95, PHE96, ALA97, ALA100, LEU101, LEU102, PHE165 and 8 more

Residues it binds most

PHE 2, LEU 2, VAL 2, ALA 2, ARG 2, LYS 2, MET 2, ASP 1 (residue and the binding sites it lines).

Found with

  • ACT · Acetate ion
  • DMS · Dimethyl sulfoxide
  • EDO · 1,2-ethanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.