MolNFT v1 · #184545 · protein + DNA
HIV-1 reverse transcriptase complex with DNA and inhibitor rmc-247
7OTN: “HIV-1 reverse transcriptase complex with DNA and inhibitor rmc-247”. X-ray diffraction, 2 ligands (1IH, MN). MolNFT v1 #184545 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7OTN
- Type
- protein + DNA
- Length
- 2,021 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P03366
- Ligands
- 1IH, MN
Structure
x-ray diffraction · 7 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C | — | protein | 555 | — | P03366 |
| D | — | protein | 411 | — | P03366 |
| A | — | protein | 556 | — | P03366 |
| B | — | protein | 412 | — | P03366 |
| E | — | dna | 23 | — | — |
| F, P | — | dna | 20 | — | — |
| T | — | dna | 24 | — | — |
Ligands and binding sites
- 1IH · (S)-2-((2-(6-amino-9H-purin-9-yl)ethyl)amino)-3-phosphonopropanoic acid · ligand · 2 copies · chains C, E, F, A, T, P
- MN · Manganese (II) ion · metal · 2 copies · chains C, A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7OTN · HIV-1 reverse transcriptase complex with DNA and inhibitor rmc-247 · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03366
- Elsewhere: RCSB PDB 7OTN · PDBe 7OTN · UniProt P03366
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