MolNFT v1 · #184026 · protein

Hsting in complex with 3',3'-C-di-araamp

7OB3 · Stimulator of interferon genes protein: “Hsting in complex with 3',3'-C-di-araamp”. X-ray diffraction, 1 ligand (V7E), 1 pocket (best druggability 0.39). MolNFT v1 #184026 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 7OB3
Type: protein
Length: 179 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Stimulator of interferon genes protein
UniProt: Q86WV6
Ligands: V7E
Pockets: 1 · best druggability 0.39

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Stimulator of interferon genes protein	protein	179	46% helix, 26% strand	Q86WV6

Ligands and binding sites

V7E · 3',3'-c-di-araAMP · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	133	0.39	0.73	22	V7E

Compared structures

7OB3 · hSTING in complex with 3',3'-c-di-araAMP · the same entry in another collection · chain A against A, TM-score 1.00
Q86WV6 · AlphaFold monomer V2.0 prediction for stimulator of interferon genes protein (Q86WV6) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q86WV6
Elsewhere: RCSB PDB 7OB3 · PDBe 7OB3 · UniProt Q86WV6

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