Structural basis for targeted P97 remodelling by aspl as prerequisite for P97 trimethylation by METTL21D

Structure

x-ray diffraction · 3 distinct chains.

Ligands and binding sites

• ATP · Adenosine-5'-triphosphate · ligand · chains B
• MG · Magnesium ion · metal
• EDO · 1,2-ethanediol · additive · 4 copies · chains B, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7OAT · Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97… · the same entry in another collection · chain A against A, TM-score 1.00
• Q9H867 · AlphaFold monomer V2.0 prediction for protein-lysine methyltransferase METTL21D (Q9H867) · a predicted model of the same protein · chain C against A, TM-score 0.98
• Q9BZE9 · AlphaFold monomer V2.0 prediction for tether containing ubx domain for GLUT4 (Q9BZE9) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q9BZE9
• Every structure of UniProt P55072
• Every structure of UniProt Q9H867
• Elsewhere: RCSB PDB 7OAT · PDBe 7OAT · UniProt Q9BZE9 · UniProt P55072 · UniProt Q9H867