UniProt Q9H867
Protein N-lysine methyltransferase METTL21D (Q9H867)
Protein N-lysine methyltransferase METTL21D (UniProt Q9H867), EC 2.1.1.-: 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9H867
- Protein
- Protein N-lysine methyltransferase METTL21D
- EC
- 2.1.1.-
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 10 · 4 records with a druggable one
Structures
7 records of Q9H867 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4LG1 | Human Methyltransferase-Like Protein 21D | x-ray diffraction | A, B, C | — | — |
| 4LG1 | Human methyltransferase-like protein 21D | x-ray diffraction | A, B, C | — | — |
| 7OAT | Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by… | x-ray diffraction | C | SAH | 4 (best 0.70) |
| 7OAT | Structural basis for targeted P97 remodelling by aspl as prerequisite for P97 trimethylation by… | x-ray diffraction | C | — | — |
| 8HL6 | Crystal structure of human valosin-containing protein methyltransferase | x-ray diffraction | A | SAM | 1 (best 0.57) |
| 8HL7 | Crystal structure of p97 N/D1 in complex with a valosin-containing protein methyltransferase | x-ray diffraction | A | SAH | 4 (best 0.71) |
| Q9H867 | AlphaFold monomer V2.0 prediction for protein-lysine methyltransferase METTL21D (Q9H867) | predicted | A | — | 1 (best 0.61) |
Ligands
Experiment against prediction
- 7OAT chain C against the predicted model Q9H867: TM-score 0.99, RMSD 0.63 Å
- 8HL7 chain A against the predicted model Q9H867: TM-score 0.99, RMSD 0.65 Å
- 7OAT chain C against the predicted model Q9H867: TM-score 0.98, RMSD 0.63 Å
- 4LG1 chain B against the predicted model Q9H867: TM-score 0.95, RMSD 1.63 Å
- 4LG1 chain B against the predicted model Q9H867: TM-score 0.95, RMSD 1.63 Å
- 4LG1 chain A against the predicted model Q9H867: TM-score 0.95, RMSD 1.73 Å
- 4LG1 chain A against the predicted model Q9H867: TM-score 0.95, RMSD 1.73 Å
- 8HL6 chain A against the predicted model Q9H867: TM-score 0.95, RMSD 1.86 Å
- 4LG1 chain C against the predicted model Q9H867: TM-score 0.94, RMSD 1.70 Å
- 4LG1 chain C against the predicted model Q9H867: TM-score 0.94, RMSD 1.70 Å
Elsewhere
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